diff --git a/CHANGELOG.md b/CHANGELOG.md
index ba25e70..0971ed8 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -10,6 +10,8 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 ### Fixed
 - Incorrect strand assignment when mapping cDNA reads is fixed by using minimap2 `-ub` instead of `-uf`.
 - Remove mention of analysis_group and type from `README.md` as they are not relevant for this workflow.
+### Changed
+- 2Ome* mod code labels are used in place of CHEBI numbers in output file names and reports for 2'-O-methylation modifications.
 
 ## [v2.0.1]
 
diff --git a/data/mod_code_labels.tsv b/data/mod_code_labels.tsv
index 65c857a..a93c57b 100644
--- a/data/mod_code_labels.tsv
+++ b/data/mod_code_labels.tsv
@@ -3,3 +3,7 @@ A:17596	inosine
 A:a	m6A
 C:m	m5C
 T:17802	pseU
+C:19228	2OmeC
+A:69426	2OmeA
+G:19229	2OmeG
+T:19227	2OmeU